Iron Man (IV) (1-35) (2005-2009) • Invincible Iron Man (IV) (1-35) (2005-2009) • Iron Man: Director of S.H.I.E.L.D. (I) (1-35) (2005-2009)

Series is named "Iron Man" and "The Invincible Iron Man" in Imprint. From #15 upwards the title on the cover is "Iron Man Director of S.H.I.E.L.D.".
Iron Man story continued from Iron Man (III) #89.

War Machines story continues in War Machine (II) #1
Series No. Date Year Title
Iron Man 1 January 2005 Extremis 1/6
Iron Man 2 February 2005 Extremis 2/6
Iron Man 3 March 2005 Extremis 3/6
Iron Man 4 October 2005 Extremis 4/6
Iron Man 5 March 2006 Extremis 5/6
Iron Man 6 May 2006 Extremis 6/6
Iron Man 7 June 2006 Execute Program 1/6
Iron Man 8 July 2006 Execute Program 2/6
Iron Man 9 August 2006 Execute Program 3/6
Iron Man 10 September 2006 Execute Program 4/6
Iron Man 11 October 2006 Execute Program 5/6
Iron Man 12 November 2006 Execute Program 6/6
Iron Man 13 December 2006 Civil War Tie-in
Iron Man 14 January 2007 Civil War Tie-in
Iron Man 15 April 2007 The Initiative Tie-in
Iron Man 16 May 2007 The Initiative Tie-in
Iron Man 17 June 2007 The Initiative Tie-in
Iron Man 18 July 2007 The Initiative Tie-in
Iron Man 19 August 2007 World War Hulk Tie-in
Iron Man (2nd print) 19 August 2007 World War Hulk Tie-in
Iron Man 20 September 2007 World War Hulk Tie-in: In absentia.
Iron Man 21 October 2007 Haunted 1/8
Iron Man 22 November 2007 Haunted 2/8
Iron Man 23 December 2007 Haunted 3/8
Iron Man 24 February 2008 Haunted 4/8
Iron Man 25 February 2008 Haunted 5/8
The origin of Iron Man (Reprint from Iron Man (I) #1)
Iron Man 26 April 2008 Haunted 6/8
Iron Man 27 May 2008 Haunted 7/8
Iron Man 28 June 2008 Haunted 8/8
Iron Man: Director of S.H.I.E.L.D. 29 July 2008 With Iron Hands 1/4
Iron Man: Director of S.H.I.E.L.D. 30 August 2008 With Iron Hands 2/4
Iron Man: Director of S.H.I.E.L.D. 31 September 2008 With Iron Hands 3/4
Iron Man: Director of S.H.I.E.L.D. 32 October 2008 With Iron Hands 4/4: Conclusion
Iron Man: Director of S.H.I.E.L.D. 33 November 2008 Secret Invasion Tie-in: War Machine Weapon of S.H.I.E.L.D. 1/3
Iron Man: Director of S.H.I.E.L.D. 34 December 2008 Secret Invasion Tie-in: War Machine Weapon of S.H.I.E.L.D. 2/3
Iron Man: Director of S.H.I.E.L.D. 35 January 2009 Secret Invasion Tie-in: War Machine Weapon of S.H.I.E.L.D. 3/3: Conclusion