Fantastic Four (IV) (500-588) (2003-2011) • The New Fantastic Four (I) (544-549) (2007)

To celebrate Marvel's first #500 issue (not counting series like Journey into Mystery (I) that was not continuous, or Captain America (I) that did not start with #1) the numbering started with Fantastic Four (I) #1 in 1961 is resumed with the issue dated September 2003; the numbering in relation to Fantastic Four (III) is given as "alternate number".
Title on cover is "The New Fantastic Four" from #544 to #549.
Fantastic Four story continued from Fantastic Four (III) #70.

The series ends with #588, the surviving F4 characters appear next in FF (I) #1.
However, a few months later the series is resumed with #600 (which could be preceeded by 588 F4 issues plus 11 issues of FF (I)).
Series No. Date Year Title
Fantastic Four 500 [71] September 2003 Unthinkable 4/4
Fantastic Four 501 [72] October 2003 5th Wheel 1/2
Fantastic Four 502 [73] October 2003 5th Wheel 2/2
Fantastic Four 503 [74] November 2003 Authoritative Action 1/6
Fantastic Four 504 [75] November 2003 Authoritative Action 2/6
Fantastic Four 505 [76] December 2003 Authoritative Acton 3/6
Fantastic Four 506 [77] January 2004 Authoritative Action 4/6
Fantastic Four 507 [78] January 2004 Authoritative Action 5/6
Fantastic Four 508 [79] February 2004 Authoritative Action 6/6
Fantastic Four 509 March 2004 Hereafter 1/3
Fantastic Four 510 April 2004 Hereafter 2/3
Fantastic Four 511 May 2004 Hereafter 3/3
Fantastic Four 512 June 2004 Spider Sense 1/2
Gone fishin'
Fantastic Four 513 July 2004 Spider Sense 2/2
Best left forgotten
Fantastic Four 514 August 2004 Dysfunctional 1/3
Fantastic Four 515 August 2004 Dysfunctional 2/3
Fantastic Four 516 September 2004 Dysfunctional 3/3
Fantastic Four 517 October 2004 Avengers Disassembled Crossover: Fourtitude 1/3
Fantastic Four 518 November 2004 Avengers Disassembled Crossover: Fourtitude 2/3
Fantastic Four 519 December 2004 Avengers Disassembled Crossover: Fourtitude 3/3
Fantastic Four 520 January 2005 Rising Storm 1/4
Fantastic Four 521 February 2005 Rising Storm 2/4
Fantastic Four 522 March 2005 Rising Storm 3/4
Fantastic Four 523 April 2005 Rising Storm 4/4
Fantastic Four 524 May 2005 Tag
Fantastic Four 525 June 2005 Dream Fever! 1/2
Fantastic Four 526 June 2005 Dream Fever! 2/2
Fantastic Four (variant cover) 527 July 2005 Distant music
Fantastic Four 528 August 2005 Random factors
Fantastic Four 529 September 2005 Appointment overdue
Fantastic Four 530 October 2005 Truth in fligth
Fantastic Four 531 November 2005 Many questions, some answered
Fantastic Four 532 December 2005 Any day now... I shall be released
Fantastic Four 533 January 2006 What happens in Vegas, stays in Vegas
Fantastic Four 534 March 2006 Shadow boxing
My dinner with Doom(bots)! (Franklin Benjamin Richards)
Fantastic Four 535 April 2006 To be this monster
Fantastic Four 536 May 2006 The Road to Civil War: The Hammer Falls 1/2
Fantastic Four 537 June 2006 The Road to Civil War: The Hammer Falls 2/2
Fantastic Four 538 August 2006 Civil War Tie-in: Street fighting
Fantastic Four 539 September 2006 Civil War Tie-in: Decisions made
Fantastic Four 540 November 2006 Civil War Tie-in: Some words can never be taken back
Fantastic Four 541 November 2006 Civil War Tie-in: Many annoying Things, none of them French
Fantastic Four 542 December 2006 Civil War Tie-in: We used to go to hyperspace just for donuts
Fantastic Four 543 January 2007 Civil War Epilogue: C'mon, Sozie, don't leave us hangin'
If this be... Anniversary! (Fantastic Four, Stan Lee)
A day at the races
The New Fantastic Four (I) (544-549) (2007)
Fantastic Four 544 May 2007 The Initiative Tie-in: Reconstruction 1/7: From the ridiculous to the sublime (but not necessarily in that order)
Fantastic Four 545 June 2007 The Initiative Tie-in: Reconstruction 2/7: Don't make me emarass you in front of your friends
Fantastic Four 546 July 2007 The Initiative Tie-in: Reconstruction 3/7: Aw, that's just crude
Fantastic Four 547 August 2007 The Initiative Tie-in: Reconstruction 4/7: Never ask her if she's wearing colored contact lenses
Fantastic Four 548 September 2007 The Initiative Tie-in: Reconstruction 5/7: Kind of an expensive test
Fantastic Four 549 October 2007 The Initiative Tie-in: Reconstruction 6/7: So i guess you're saying the honeymoon's over
Fantastic Four (I cont.) (500-588) (2003-2011)
Fantastic Four 550 November 2007 The Initiative Tie-in: Reconstruction 7/7: Should Eternity perish
Fantastic Four 551 January 2008 Epilogue 1/4: The Beginning of the End
Fantastic Four 552 January 2008 Epilogue 2/4: The middle of the end
Fantastic Four 553 March 2008 Epilogue 3/4: The end
Fantastic Four 554 April 2008 World's Greatest 1/4
Fantastic Four (Newsstand) 554 April 2008 World's Greatest 1/4
Fantastic Four 555 May 2008 World's Greatest 2/4
Fantastic Four 556 June 2008 World's Greatest 3/4
Fantastic Four 557 July 2008 World's Greatest 4/4 (Story continues in part from Mighty Avengers #11)
Fantastic Four 558 August 2008 Death of the Invisible Woman 1/5: The New Defenders
Fantastic Four 559 September 2008 Death of the Invisible Woman 2/5: The hooded man
Fantastic Four 560 November 2008 Death of the Invisible Woman 3/5: Futureshock
Fantastic Four 561 January 2009 Death of the Invisible Woman 4/5: The Galactus engine
Fantastic Four (Newsstand) 561 January 2009 Death of the Invisible Woman 4/5: The Galactus engine
Fantastic Four 562 February 2009 Death of the Invisible Woman 5/5: Requiem
Fantastic Four 563 March 2009 Mr. and Mrs. Thing
Fantastic Four 564 April 2009 The Christmas monster
Fantastic Four 565 May 2009 Don't eat Valeria!
Fantastic Four 566 July 2009 Doom's Master 1/4
Fantastic Four 567 July 2009 Doom's Master 2/4
Fantastic Four 568 August 2009 Doom's Master 3/4
Fantastic Four 569 September 2009 Doom's Master 4/4
Fantastic Four 570 October 2009 Solve Everything 1/3
Fantastic Four 571 November 2009 Solve Everything 2/3
Fantastic Four 572 December 2009 Solve Everything 3/3: Conclusion
Fantastic Four 573 January 2010 Adventures on Nu-World
Fantastic Four 574 February 2010 Days of future Franklin!
Fantastic Four 575 March 2010 Prime Elements 1/4: The abandoned city of the High Evolutionary
Fantastic Four 576 April 2010 Prime Elements 2/4: The old kings of Atlantis
Fantastic Four 577 May 2010 Prime Elements 3/4: Universal Inhumans
Fantastic Four 578 June 2010 Prime Elements 4/4: The cult of the Negative Zone
Fantastic Four 579 July 2010 The Heroic Age Tie-in: The Future Foundation
Fantastic Four 580 August 2010 The Heroic Age Tie-in: The Franktastic Four
Fantastic Four 581 September 2010 The Heroic Age Tie-in: When everything's lost, the battle is won...
Fantastic Four 582 October 2010 The Heroic Age Tie-in: ...Because of all these things I've done.
Fantastic Four 583 November 2010 Three 1/5: In Latveria, the flowers bloom in winter
Fantastic Four 584 December 2010 Three 2/5: Congratulations, Mister Grimm. You're handsome again!
Fantastic Four 585 January 2011 Three 3/5: The kings of Atlantis!
Fantastic Four 586 February 2011 Three 4/5: World-eater!
Fantastic Four 587 March 2011 Three 5/5: The last stand!
Fantastic Four 588 April 2011 Three Epilogue: Month of mourning
Uncles (Franklin Benjamin Richards, Spider-Man)